pubmed-article:3503759 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3503759 | lifeskim:mentions | umls-concept:C0162871 | lld:lifeskim |
pubmed-article:3503759 | lifeskim:mentions | umls-concept:C0600599 | lld:lifeskim |
pubmed-article:3503759 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:3503759 | pubmed:dateCreated | 1988-12-21 | lld:pubmed |
pubmed-article:3503759 | pubmed:abstractText | The possible genetic predisposition to abdominal aortic aneurysm was investigated by recording the family history from 60 consecutive patients presenting for aneurysm repair. Twenty patients, age 63.2 +/- 9.3 years, had at least one first degree relative with abdominal aortic aneurysm. Thirty six patients, age 69.6 +/- 6.3 years, knew of no aortic aneurysm amongst first degree relatives and four patients could not give a full family history. A total of 25 among 320 first degree relatives (8%) or 14 amongst 192 siblings (7%) had an abdominal aortic aneurysm. Both the younger age of presentation (P less than 0.01) and the concentration of women amongst those with a positive family history argue for multifactorial inheritance of abdominal aortic aneurysm, with the genetic component calculated as approximately 70%. These same factors suggest that it might be worthwhile screening for aneurysmal disease the sibling smokers of female and younger male probands. | lld:pubmed |
pubmed-article:3503759 | pubmed:language | eng | lld:pubmed |
pubmed-article:3503759 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3503759 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3503759 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3503759 | pubmed:month | Feb | lld:pubmed |
pubmed-article:3503759 | pubmed:issn | 0950-821X | lld:pubmed |
pubmed-article:3503759 | pubmed:author | pubmed-author:PowellJ TJT | lld:pubmed |
pubmed-article:3503759 | pubmed:author | pubmed-author:GreenhalghR... | lld:pubmed |
pubmed-article:3503759 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3503759 | pubmed:volume | 1 | lld:pubmed |
pubmed-article:3503759 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3503759 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3503759 | pubmed:pagination | 29-31 | lld:pubmed |
pubmed-article:3503759 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:3503759 | pubmed:meshHeading | pubmed-meshheading:3503759-... | lld:pubmed |
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pubmed-article:3503759 | pubmed:meshHeading | pubmed-meshheading:3503759-... | lld:pubmed |
pubmed-article:3503759 | pubmed:year | 1987 | lld:pubmed |
pubmed-article:3503759 | pubmed:articleTitle | Multifactorial inheritance of abdominal aortic aneurysm. | lld:pubmed |
pubmed-article:3503759 | pubmed:affiliation | Department of Surgery, Charing Cross and Westminster Medical School, London, UK. | lld:pubmed |
pubmed-article:3503759 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3503759 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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