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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-2-2
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pubmed:abstractText |
Fresh human brain-tumor samples were assayed for their plasminogen activator (PA) content. Specific molecular weight patterns were identified for each of five common brain tumors and for normal brain, suggesting a cell-specific origin of the various PA forms. Malignant tumors contained higher PA activity and a larger number of molecular weight patterns than benign tumors, with the exception of acoustic neurinomas. Irradiated tumors contained lower PA activity than nonirradiated tumors. Finally, a slight but definite correlation between brain edema and PA activity was detected. The future role of brain-tumor PA's for diagnostic and therapeutic purposes is discussed.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0022-3085
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
68
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
73-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3335914-Astrocytoma,
pubmed-meshheading:3335914-Brain,
pubmed-meshheading:3335914-Brain Edema,
pubmed-meshheading:3335914-Brain Neoplasms,
pubmed-meshheading:3335914-Glioma,
pubmed-meshheading:3335914-Humans,
pubmed-meshheading:3335914-Meningioma,
pubmed-meshheading:3335914-Molecular Weight,
pubmed-meshheading:3335914-Neuroma, Acoustic,
pubmed-meshheading:3335914-Plasminogen Activators
|
pubmed:year |
1988
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pubmed:articleTitle |
Plasminogen activator activity and molecular weight patterns in human brain tumors.
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pubmed:affiliation |
Department of Neurosurgery, University of Cincinnati College of Medicine, Ohio.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|