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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1989-3-29
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pubmed:abstractText |
Between March, 1985 and April, 1987, 25 orthotopic heart transplantations were performed in 20 men and 5 women aged from 17 to 58 years (mean 42 years) on account of cardiomyopathy (n = 15), ischaemic heart disease (n = 6) or miscellaneous lesions (n = 4). The immunosuppressive treatment consisted of antilymphocyte serum and corticosteroids during 10 days; cyclosporine was introduced on the 7th day and continued thereafter in association with low-dose corticosteroid therapy. Endomyocardial biopsies were performed. Acute rejection, responsible for 2 deaths (one on the 10th day, the other in the 10th week), usually occurred within the first 3 months. Infections were frequent and often serious, resulting in one death in the 7th week. One out of patients had to be treated for arterial hypertension, and 3 patients presented with renal impairment (blood creatinine over 200 mumoles/l). The actuarial survival rate at 2 years is 84 p. 100. More than one-half of the patients have resumed social and occupational activities.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-9683
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1369-75
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pubmed:dateRevised |
2009-2-13
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pubmed:meshHeading |
pubmed-meshheading:3147629-Actuarial Analysis,
pubmed-meshheading:3147629-Adolescent,
pubmed-meshheading:3147629-Adrenal Cortex Hormones,
pubmed-meshheading:3147629-Adult,
pubmed-meshheading:3147629-Cardiomyopathies,
pubmed-meshheading:3147629-Clinical Protocols,
pubmed-meshheading:3147629-Female,
pubmed-meshheading:3147629-Follow-Up Studies,
pubmed-meshheading:3147629-France,
pubmed-meshheading:3147629-Graft vs Host Disease,
pubmed-meshheading:3147629-Heart Transplantation,
pubmed-meshheading:3147629-Humans,
pubmed-meshheading:3147629-Immunosuppressive Agents,
pubmed-meshheading:3147629-Male,
pubmed-meshheading:3147629-Middle Aged,
pubmed-meshheading:3147629-Postoperative Complications
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pubmed:year |
1988
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pubmed:articleTitle |
[Cardiac transplantation at the University Hospital Center of Nantes. 2 years' experience].
|
pubmed:affiliation |
Service de cardiologie, hôpital Laënnec, Nantes.
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pubmed:publicationType |
Journal Article,
English Abstract
|