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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1988-5-31
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pubmed:abstractText |
The chronic intracerebroventricular infusion of the somatostatin analogue SMS 201-995 resulted in a significant increase in daily food intake which was accompanied by an unexpected body weight loss. The neutralisation of central somatostatin using a specific somatostatin antiserum resulted in a significant decrease in daily food intake. These results suggest that endogenous somatostatin in the brain can drive feeding behavior and alter body weight.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0196-9781
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
211-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2896344-Animals,
pubmed-meshheading:2896344-Body Weight,
pubmed-meshheading:2896344-Cerebral Ventricles,
pubmed-meshheading:2896344-Eating,
pubmed-meshheading:2896344-Feeding Behavior,
pubmed-meshheading:2896344-Immune Sera,
pubmed-meshheading:2896344-Infusions, Parenteral,
pubmed-meshheading:2896344-Male,
pubmed-meshheading:2896344-Octreotide,
pubmed-meshheading:2896344-Rats,
pubmed-meshheading:2896344-Rats, Inbred Strains,
pubmed-meshheading:2896344-Somatostatin
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pubmed:articleTitle |
Food intake in rats is increased by intracerebroventricular infusion of the somatostatin analogue SMS 201-995 and is decreased by somatostatin antiserum.
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pubmed:affiliation |
CNRS UA 637, Neurobiologie des Régulations, Collège de France, Paris.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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