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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1986-5-5
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pubmed:abstractText |
We investigated the serial expression of c-myc oncogene during differentiation of normal human burst-forming unit, erythroid (BFU-E), in vitro, together with the replating efficiency and the expression of transferrin receptors. We found that the c-myc oncogene was expressed in the early progeny of BFU-E and that this expression decreased during erythroid differentiation. This change of the c-myc expression was well correlated to changes in the replating efficiency and the expression of transferrin receptors. These observations indicate that the c-myc oncogene probably has a physiological role in normal human hematopoiesis as well as leukemic hematopoiesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0006-291X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
13
|
pubmed:volume |
135
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
521-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2421720-Cell Differentiation,
pubmed-meshheading:2421720-Cell Division,
pubmed-meshheading:2421720-Colony-Forming Units Assay,
pubmed-meshheading:2421720-Erythrocytes,
pubmed-meshheading:2421720-Gene Expression Regulation,
pubmed-meshheading:2421720-Globins,
pubmed-meshheading:2421720-Hematopoiesis,
pubmed-meshheading:2421720-Humans,
pubmed-meshheading:2421720-Oncogenes,
pubmed-meshheading:2421720-RNA,
pubmed-meshheading:2421720-Receptors, Cell Surface,
pubmed-meshheading:2421720-Receptors, Transferrin
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pubmed:year |
1986
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pubmed:articleTitle |
Expression of c-myc oncogene during differentiation of human burst-forming unit, erythroid (BFU-E).
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|