Linked Life Data

2181163

Source:http://linkedlifedata.com/resource/pubmed/id/2181163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-5-7
pubmed:abstractText
The serum levels of the carcinoembryonic antigen (CEA) and the beta 2-microglobulin (beta 2M) have been examined in 55 patients with a head and neck squamous cell carcinoma, and the squamous cell carcinoma-related antigen (SCC) levels were also detected in 36 of these subjects. With the advancement of the T-stage, an elevation in both the original SCC and the beta 2M levels was seen, though the level of the CEA did not relate with the T-stage. In three markers, the SCC clearly changed, in relation to the clinical conditions. About two-thirds (63%) of the advanced tumors (T 3 + 4) had a higher SCC level than the cut-off value (1.5 ng/ml), while levels in most early carcinomas did not reach the border line. In cases that were successfully treated, elevated SCC levels were lowered to below 1.5 ng/ml without exception, whereas the SCC values of cases with a bad prognosis remained at a high level. Further, the consecutive elevation of the beta 2M levels was observed even after the treatments. From these results, it seems that SCC combined with CEA appears useful for the diagnosis and monitoring of head and neck squamous cell carcinomas.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0021-4949
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
458-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Clinical evaluation of tumor markers in head and neck squamous cell carcinomas].
pubmed:affiliation
Dept. of Oral Surgery, Kochi Medical School.
pubmed:publicationType
Journal Article, English Abstract