Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-5-2
pubmed:abstractText
This study was conducted to investigate the association between Helicobacter pylori (H. pylori) infection and the lipid profile among elderly Koreans. A total of 462 subjects (mean age 66.2 ± 7.6 yr, 84% males) who underwent health check-up were investigated. Each subject underwent gastroduodenoscopy with gastric mucosal biopsy, and H. pylori infection was determined by histopathological examination using the updated Sydney System score. The presence of H. pylori infection was significantly associated with the elevated serum levels of total cholesterol and low density lipoprotein (LDL) cholesterol (P < 0.05 for each) in univariate analysis. H. pylori infection was not associated with triglyceride and high density lipoprotein (HDL) cholesterol levels (P > 0.05 for each). After controlling confounders, multiple logistic regression analysis showed that the odds ratio of H. pylori infection for high LDL cholesterol level (> 140 mg/dL) was 3.113 (95% confidence interval, 1.364-7.018; P = 0.007). There were no significant associations between the presence of H. pylori infection and elevated total cholesterol levels (> 200 mg/dL) in this model (P = 0.586). The results of this study demonstrate that H. pylori infection is associated with the elevated serum LDL cholesterol levels in elderly Koreans, supporting the hypothesis that H. pylori plays a role in promoting atherosclerosis by modifying lipid metabolism.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-10511283, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-11231924, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-11792334, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-11966866, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-12849867, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-14715353, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-1520782, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-15505430, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-15586651, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-15993502, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-16047464, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-17939331, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-18649137, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-19086952, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-19237832, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-20030806, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-20134372, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-2030153, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-20610892, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-5824173, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-8697159, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-8827022, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-9552950, http://linkedlifedata.com/resource/pubmed/commentcorrection/21532857-9920523
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1598-6357
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
654-8
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Helicobacter pylori infection is associated with elevated low density lipoprotein cholesterol levels in elderly Koreans.
pubmed:affiliation
Armed Forces Seoul Hospital, Seoul, Korea.
pubmed:publicationType
Journal Article