Linked Life Data

21360112

Source:http://linkedlifedata.com/resource/pubmed/id/21360112

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2011-5-3
pubmed:abstractText
Although there is general agreement that symptomatic aortic stenosis (AS) requires urgent surgery, it remains controversial when to operate on asymptomatic but nevertheless severe AS. Current practice guidelines recommend valve replacement in patients in asymptomatic when the systolic left ventricular function is found to be reduced without other explanation. Otherwise, surgery should be or at least may be considered (recommendation classes IIa or IIb) in asymptomatic patients with severe AS and an abnormal exercise test, a high likelihood of rapid progression, or very severe AS in the presence of low surgical risk. This article reviews recent publications evaluating early elective surgery versus watchful waiting as recommended by current guidelines. The second focus of this review is on new insights on predictors of outcome in asymptomatic AS that may improve timing of surgery and therefore deserve to be considered in future recommendations for the treatment of this difficult patient group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1534-3170
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-5
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Asymptomatic aortic stenosis: when to operate?
pubmed:affiliation
Adult Congenital and Valvular Heart Disease Center, Department of Cardiology and Angiology, University Hospital Muenster, Albert-Schweitzer-Str. 33, 48149 Muenster, Germany.
pubmed:publicationType
Journal Article, Review