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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2010-9-8
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pubmed:abstractText |
Autism is a common heritable neurodevelopmental disorder with complex etiology. Several genome-wide linkage and association scans have been carried out to identify regions harboring genes related to autism or autism spectrum disorders, with mixed results. Given the overlap in autism features with genetic abnormalities known to be associated with imprinting, one possible reason for lack of consistency would be the influence of parent-of-origin effects that may mask the ability to detect linkage and association.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:meshHeading |
pubmed-meshheading:20824079-Adolescent,
pubmed-meshheading:20824079-Adult,
pubmed-meshheading:20824079-Autistic Disorder,
pubmed-meshheading:20824079-Child,
pubmed-meshheading:20824079-Chromosome Mapping,
pubmed-meshheading:20824079-Female,
pubmed-meshheading:20824079-Genetic Linkage,
pubmed-meshheading:20824079-Genetic Predisposition to Disease,
pubmed-meshheading:20824079-Genome-Wide Association Study,
pubmed-meshheading:20824079-Genomic Imprinting,
pubmed-meshheading:20824079-Humans,
pubmed-meshheading:20824079-Male,
pubmed-meshheading:20824079-Middle Aged,
pubmed-meshheading:20824079-Pedigree,
pubmed-meshheading:20824079-Polymorphism, Single Nucleotide,
pubmed-meshheading:20824079-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Parent-of-origin effects in autism identified through genome-wide linkage analysis of 16,000 SNPs.
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pubmed:affiliation |
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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