Linked Life Data

20562079

Source:http://linkedlifedata.com/resource/pubmed/id/20562079

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-6-21
pubmed:abstractText
A manageable and reproducible large animal model of human-like coronary atherosclerosis is lacking but highly needed for translational research in percutaneous coronary interventions and imaging. Farm pigs with familial hypercholesterolaemia develop advanced atherosclerosis in two to three years but then weigh >200 kg making them impractical and costly. We aimed at down-sizing this pig and accelerating coronary plaque development to make the model more useful and affordable.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1969-6213
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Familial hypercholesterolaemic downsized pig with human-like coronary atherosclerosis: a model for preclinical studies.
pubmed:affiliation
Atherosclerosis Research Unit, Department of Cardiology, Aarhus University Hospital (Skejby) and Institute of Clinical Medicine, Aarhus University, Denmark. troels.thim@ki.au.dk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't