20508203

Source:http://linkedlifedata.com/resource/pubmed/id/20508203

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0003591, umls-concept:C0004153, umls-concept:C0024432, umls-concept:C0026809, umls-concept:C0028066, umls-concept:C0205263, umls-concept:C0449258, umls-concept:C1335238, umls-concept:C1879547
pubmed:issue	8
pubmed:dateCreated	2010-7-15
pubmed:abstractText	Nifedipine, an L-type calcium channel blocker, protects against the progression of atherosclerosis. We investigated the molecular basis of the antiatherosclerotic effect of nifedipine in macrophages and apolipoprotein E-deficient mice.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9505803
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/1,2-bis(2-aminophenoxy)ethane..., http://linkedlifedata.com/resource/pubmed/chemical/ATP binding cassette transporter 1, http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Amlodipine, http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channel Blockers, http://linkedlifedata.com/resource/pubmed/chemical/Cardiovascular Agents, http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Chelating Agents, http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2, http://linkedlifedata.com/resource/pubmed/chemical/Egtazic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Flavonoids, http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Nifedipine, http://linkedlifedata.com/resource/pubmed/chemical/PD 98059, http://linkedlifedata.com/resource/pubmed/chemical/PPAR gamma, http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/lipopolysaccharide, Escherichia...
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1524-4636
pubmed:author	pubmed-author:ArakiEiichiE, pubmed-author:FukudaKazukiK, pubmed-author:IshiiNorioN, pubmed-author:KawadaTeruoT, pubmed-author:Kim-MitsuyamaShokeiS, pubmed-author:KinoshitaHiroyukiH, pubmed-author:MatsumuraTakeshiT, pubmed-author:MiyamuraNobuhiroN, pubmed-author:MotoshimaHiroyukiH, pubmed-author:NakaoSayaS, pubmed-author:NishikawaTakeshiT, pubmed-author:SenokuchiTakafumiT, pubmed-author:TakeyaMotohiroM, pubmed-author:TsutsumiAtsuyukiA
pubmed:issnType	Electronic
pubmed:volume	30
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1598-605
pubmed:meshHeading	pubmed-meshheading:20508203-ATP-Binding Cassette Transporters, pubmed-meshheading:20508203-Amlodipine, pubmed-meshheading:20508203-Animals, pubmed-meshheading:20508203-Apolipoproteins E, pubmed-meshheading:20508203-Atherosclerosis, pubmed-meshheading:20508203-Calcium Channel Blockers, pubmed-meshheading:20508203-Cardiovascular Agents, pubmed-meshheading:20508203-Cells, Cultured, pubmed-meshheading:20508203-Chelating Agents, pubmed-meshheading:20508203-Chemokine CCL2, pubmed-meshheading:20508203-Disease Models, Animal, pubmed-meshheading:20508203-Disease Progression, pubmed-meshheading:20508203-Dose-Response Relationship, Drug, pubmed-meshheading:20508203-Egtazic Acid, pubmed-meshheading:20508203-Enzyme Activation, pubmed-meshheading:20508203-Flavonoids, pubmed-meshheading:20508203-Humans, pubmed-meshheading:20508203-Lipopolysaccharides, pubmed-meshheading:20508203-Macrophages, Peritoneal, pubmed-meshheading:20508203-Male, pubmed-meshheading:20508203-Mice, pubmed-meshheading:20508203-Mice, Inbred C3H, pubmed-meshheading:20508203-Mice, Knockout, pubmed-meshheading:20508203-Mitogen-Activated Protein Kinase 1, pubmed-meshheading:20508203-Mitogen-Activated Protein Kinase 3, pubmed-meshheading:20508203-Mutation, pubmed-meshheading:20508203-Nifedipine, pubmed-meshheading:20508203-PPAR gamma, pubmed-meshheading:20508203-Phosphorylation, pubmed-meshheading:20508203-Protein Kinase Inhibitors, pubmed-meshheading:20508203-RNA, Messenger, pubmed-meshheading:20508203-RNA Interference, pubmed-meshheading:20508203-Time Factors, pubmed-meshheading:20508203-Transfection
pubmed:year	2010
pubmed:articleTitle	Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.
pubmed:affiliation	Department of Metabolic Medicine, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't