Source:http://linkedlifedata.com/resource/pubmed/id/20198227
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2010-3-3
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pubmed:abstractText |
Reduction of anticancer prodrugs such as ctc-[PtCl(2)(CH(3)CO(2))(2)(NH(3))(Am)] can yield three products in addition to the expected cis-[PtCl(2)(NH(3))(Am)]. A possible explanation is that reduction proceeds by several pathways where in addition to the loss of two axial ligands, one axial (acetato) and one equatorial (chlorido) ligand, or two equatorial ligands are eliminated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1364-548X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
21
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1842-4
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
New reduction pathways for ctc-[PtCl2(CH3CO2)2(NH3)(Am)] anticancer prodrugs.
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pubmed:affiliation |
Department of Medicinal Chemistry and Natural Products, Institute of Drug Research, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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