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19950268
Source:
http://linkedlifedata.com/resource/pubmed/id/19950268
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0003873
,
umls-concept:C0016030
,
umls-concept:C1550315
,
umls-concept:C2613367
pubmed:issue
12
pubmed:dateCreated
2009-12-16
pubmed:abstractText
Rheumatoid arthritis synovial fibroblasts (RASFs) are phenotypically activated and aggressive. We undertook this study to investigate whether the intrinsic activation of RASFs is due to global genomic hypomethylation, an epigenetic modification.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/0370605
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Azacitidine
,
http://linkedlifedata.com/resource/pubmed/chemical/DNA (Cytosine-5-)-Methyltransferase
,
http://linkedlifedata.com/resource/pubmed/chemical/DNA...
,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0004-3591
pubmed:author
pubmed-author:GayRenate ERE
,
pubmed-author:GaySteffenS
,
pubmed-author:KarouzakisEmmanuelE
,
pubmed-author:MichelBeat ABA
,
pubmed-author:NeidhartMichelM
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3613-22
pubmed:meshHeading
pubmed-meshheading:19950268-Arthritis, Rheumatoid
,
pubmed-meshheading:19950268-Azacitidine
,
pubmed-meshheading:19950268-Cells, Cultured
,
pubmed-meshheading:19950268-DNA (Cytosine-5-)-Methyltransferase
,
pubmed-meshheading:19950268-DNA Methylation
,
pubmed-meshheading:19950268-Enzyme Inhibitors
,
pubmed-meshheading:19950268-Fibroblasts
,
pubmed-meshheading:19950268-Gene Expression
,
pubmed-meshheading:19950268-Gene Silencing
,
pubmed-meshheading:19950268-Humans
,
pubmed-meshheading:19950268-Long Interspersed Nucleotide Elements
,
pubmed-meshheading:19950268-Oligonucleotide Array Sequence Analysis
,
pubmed-meshheading:19950268-Osteoarthritis
,
pubmed-meshheading:19950268-Synovial Membrane
pubmed:year
2009
pubmed:articleTitle
DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.
pubmed:affiliation
Zurich Center of Integrative Human Physiology, University Hospital, Zurich, Switzerland.
pubmed:publicationType
Journal Article