Linked Life Data

19713413

Source:http://linkedlifedata.com/resource/pubmed/id/19713413

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-8-28
pubmed:abstractText
Angiotensin-converting enzyme (ACE) is thought to influence the activity of the hypothalamic-pituitary-adrenocortical system, which shows hyperactivity in the majority of patients with major depressive disorder (MDD). This study aimed at determining an association between two single nucleotide polymorphisms (SNPs) (rs4291;-240A/T and rs4292;-93T/C) of the ACE gene promoter and MDD in northeastern Thais.Subjects and methods. In the present case-control study, genotyping of 187 unrelated patients with MDD (44.89+/-12.92 years) and 207 unrelated healthy controls (41.34+/-9.76 years) from the northeastern part of Thailand was performed using polymerase chain reaction-restriction fragment length polymorphism technique.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1752-8976
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-84
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Association of angiotensin-converting enzyme gene promoter single nucleotide polymorphisms and haplotype with major depression in a northeastern Thai population.
pubmed:affiliation
Department of Clinicals Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't