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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2009-8-25
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pubmed:abstractText |
The Wnt signaling pathway has been implicated in colon and other cancers. Nevertheless, few or no mutations of CTNNB1 (beta-catenin) have so far been described in brain cancer. We therefore examined the prevalence of constitutive activation of the Wnt signaling pathway in brain cancer specimens as well as cancer cell lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0942-0940
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
151
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1107-11
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19582367-Brain Neoplasms,
pubmed-meshheading:19582367-Carcinoma,
pubmed-meshheading:19582367-Catalytic Domain,
pubmed-meshheading:19582367-Cell Line, Tumor,
pubmed-meshheading:19582367-DNA Mutational Analysis,
pubmed-meshheading:19582367-Exons,
pubmed-meshheading:19582367-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19582367-Gene Frequency,
pubmed-meshheading:19582367-Genetic Markers,
pubmed-meshheading:19582367-Genetic Predisposition to Disease,
pubmed-meshheading:19582367-Genetic Testing,
pubmed-meshheading:19582367-Humans,
pubmed-meshheading:19582367-Lung Neoplasms,
pubmed-meshheading:19582367-Mutation,
pubmed-meshheading:19582367-Neoplasm Metastasis,
pubmed-meshheading:19582367-Phosphorylation,
pubmed-meshheading:19582367-Signal Transduction,
pubmed-meshheading:19582367-Transcriptional Activation,
pubmed-meshheading:19582367-Tumor Markers, Biological,
pubmed-meshheading:19582367-Wnt Proteins,
pubmed-meshheading:19582367-beta Catenin
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pubmed:year |
2009
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pubmed:articleTitle |
CTNNB1 (beta-catenin) mutation is rare in brain tumours but involved as a sporadic event in a brain metastasis.
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pubmed:affiliation |
Department of Medical Technology, Fooyin University, Kaohsiung, Taiwan, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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