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rdf:type |
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lifeskim:mentions |
umls-concept:C0015127,
umls-concept:C0018270,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0034843,
umls-concept:C0086418,
umls-concept:C0205314,
umls-concept:C0679622,
umls-concept:C1257751,
umls-concept:C1314792,
umls-concept:C1332838,
umls-concept:C1424663
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-20
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pubmed:abstractText |
Thyroid hormone receptors (TRs) are ligand-dependent transcription factors with a major impact on erythroid cell development. Here we investigated TR activity on red cell gene expression and identified TR target genes. The impact of the TR target gene GAR22 (growth arrest-specific 2 [GAS2]-related gene on chromosome 22) on red cell differentiation was determined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/GAS2L1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/KLF9 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Kruppel-Like Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Microfilament Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Thyroid Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Triiodothyronine,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1873-2399
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
539-548.e4
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pubmed:meshHeading |
pubmed-meshheading:19375645-Cell Cycle,
pubmed-meshheading:19375645-Cell Differentiation,
pubmed-meshheading:19375645-Cells, Cultured,
pubmed-meshheading:19375645-Erythroid Precursor Cells,
pubmed-meshheading:19375645-Humans,
pubmed-meshheading:19375645-Kruppel-Like Transcription Factors,
pubmed-meshheading:19375645-Ligands,
pubmed-meshheading:19375645-Microfilament Proteins,
pubmed-meshheading:19375645-Receptors, Thyroid Hormone,
pubmed-meshheading:19375645-Triiodothyronine,
pubmed-meshheading:19375645-Tumor Suppressor Proteins
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pubmed:year |
2009
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pubmed:articleTitle |
GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells.
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pubmed:affiliation |
Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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