| pubmed-article:1936990 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C0040223 | lld:lifeskim |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C0017255 | lld:lifeskim |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C1709305 | lld:lifeskim |
| pubmed-article:1936990 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:1936990 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:1936990 | pubmed:dateCreated | 1991-12-16 | lld:pubmed |
| pubmed-article:1936990 | pubmed:abstractText | The yeast HO gene is transcribed transiently during G1 as cells undergo START. START-specific HO activation requires two proteins, SWI4 and SWI6, which act via a motif (CACGA4) repeated up to 10 times within the URS2 region of the HO promoter. We identified a DNA-binding activity containing SWI4 and SWI6 that recognizes the CACGA4 sequences within URS2. Two forms of SWI4,6-DNA complexes called L and U can be distinguished by their electrophoretic mobility. L complexes can be detected at all stages of the cell cycle, but U complexes are only detected in cells that have undergone START. The formation of U complexes may be the trigger of HO activation. The SWI6 protein is concentrated in the nucleus throughout G1, but at some point in S or G2 significant amounts accumulate in the cytoplasm. This change in cellular location of the SWI6 protein might contribute to the turnoff of HO transcription after cells have undergone START. | lld:pubmed |
| pubmed-article:1936990 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1936990 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1936990 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1936990 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1936990 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1936990 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1936990 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:1936990 | pubmed:author | pubmed-author:NasmythKK | lld:pubmed |
| pubmed-article:1936990 | pubmed:author | pubmed-author:TebbGG | lld:pubmed |
| pubmed-article:1936990 | pubmed:author | pubmed-author:MurogaSS | lld:pubmed |
| pubmed-article:1936990 | pubmed:author | pubmed-author:LydallDD | lld:pubmed |
| pubmed-article:1936990 | pubmed:author | pubmed-author:TabaM RMR | lld:pubmed |
| pubmed-article:1936990 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1936990 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:1936990 | pubmed:geneSymbol | HO | lld:pubmed |
| pubmed-article:1936990 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1936990 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1936990 | pubmed:pagination | 2000-13 | lld:pubmed |
| pubmed-article:1936990 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:1936990 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1936990 | pubmed:articleTitle | Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast. | lld:pubmed |
| pubmed-article:1936990 | pubmed:affiliation | Research Institute of Molecular Pathology, Vienna, Austria. | lld:pubmed |
| pubmed-article:1936990 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1936990 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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