Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-2-13
pubmed:abstractText
Multilocus sequence typing (MLST) data have revealed many insights into the global epidemiology of Staphylococcus aureus but, with notable exceptions such as Japan, the evidence from most Asian countries is currently limited. Here we have applied MLST to 132 hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates collected in mainland China in 2002. In all, 102 isolates were recovered from a single tertiary hospital in Guangzhou, South China, and the remaining 30 isolates were recovered from six metropolitan tertiary hospitals from geographically diverse districts corresponding to a total area of more than 2 million km2. The data reveal a striking predominance throughout mainland China of a single clonal lineage, ST 239, which accounts for 97% of the 132 isolates. These data support more limited evidence from previous studies suggesting the widespread predominance of ST 239 throughout hospitals in China, a pattern which possibly extends to the whole of continental Asia. Staphylococcal chromosome cassette mec (SCCmec) typing confirmed the homogeneity of the ST 239 isolates, with the vast majority corresponding to the Hungarian clone (ST 239-III).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0195-6701
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-55
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Predominance of the Hungarian clone (ST 239-III) among hospital-acquired meticillin-resistant Staphylococcus aureus isolates recovered throughout mainland China.
pubmed:affiliation
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study