19143814

Source:http://linkedlifedata.com/resource/pubmed/id/19143814

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0019721, umls-concept:C0035647, umls-concept:C0205147, umls-concept:C0332281, umls-concept:C0456387, umls-concept:C1708726
pubmed:dateCreated	2009-1-15
pubmed:abstractText	Several studies have indicated that genes in the human leucocyte antigen (HLA) region additional to the HLA class II DRB1-DQB1 contribute to type 1 diabetes (T1D) susceptibility. The aim of this study was to assess if markers in the class III Major Histocompatibility Complex (MHC) region are associated with T1D after accounting for linkage disequilibrium (LD) with DRB1-DQB1.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/N01-AI-40076, http://linkedlifedata.com/resource/pubmed/grant/U01 DK062418, http://linkedlifedata.com/resource/pubmed/grant/U01 DK062418-06
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/100883645
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/HLA Antigens, http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ Antigens, http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQ beta-Chains, http://linkedlifedata.com/resource/pubmed/chemical/HLA-DQB1 antigen, http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens, http://linkedlifedata.com/resource/pubmed/chemical/HLA-DRB1 Chains
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	1463-1326
pubmed:author	pubmed-author:ThomsonGG, pubmed-author:Type 1 Diabetes Genetics Consortium, pubmed-author:ValdesA MAM
pubmed:issnType	Electronic
pubmed:volume	11 Suppl 1
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	46-52
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:19143814-Diabetes Mellitus, Type 1, pubmed-meshheading:19143814-European Continental Ancestry Group, pubmed-meshheading:19143814-Genetic Predisposition to Disease, pubmed-meshheading:19143814-Genotype, pubmed-meshheading:19143814-HLA Antigens, pubmed-meshheading:19143814-HLA-DQ Antigens, pubmed-meshheading:19143814-HLA-DQ beta-Chains, pubmed-meshheading:19143814-HLA-DR Antigens, pubmed-meshheading:19143814-HLA-DRB1 Chains, pubmed-meshheading:19143814-Humans, pubmed-meshheading:19143814-Major Histocompatibility Complex, pubmed-meshheading:19143814-Pedigree, pubmed-meshheading:19143814-Polymorphism, Single Nucleotide
pubmed:year	2009
pubmed:articleTitle	Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1.
pubmed:affiliation	Twin Research Unit, King's College London, St Thomas' Hospital, London, UK. ana.valdes@kcl.ac.uk
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study, Research Support, N.I.H., Extramural