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pubmed-article:19118031pubmed:abstractTextProgression to the castration-resistant state is the incurable and lethal end stage of prostate cancer, and there is strong evidence that androgen receptor (AR) still plays a central role in this process. We hypothesize that knocking down AR will have a major effect on inhibiting growth of castration-resistant tumors.lld:pubmed
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pubmed-article:19118031pubmed:articleTitleIn vivo knockdown of the androgen receptor results in growth inhibition and regression of well-established, castration-resistant prostate tumors.lld:pubmed
pubmed-article:19118031pubmed:affiliationProstate Center at Vancouver General Hospital and Department of Urologic Sciences, University of British Columbia, British Columbia, Canada.lld:pubmed
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