Source:http://linkedlifedata.com/resource/pubmed/id/18836731
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-1-9
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pubmed:abstractText |
Integrins such as alpha(2)beta(1), alpha(IIb)beta(3), and alpha(v)beta(3) have been suggested as key players for cancer development and progression. Several polymorphisms affecting these molecules, two in integrin alpha(2) (ITGA2 807C>T and 1648G>A) and one in beta(3) (ITGB3 176T>C), influence their levels, structure, and possibly their function. To analyze the role of ITGA2 and ITGB3 polymorphisms for colorectal cancer risk and clinical presentation, we performed a case-control study.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1432-1262
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
159-63
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pubmed:meshHeading |
pubmed-meshheading:18836731-Case-Control Studies,
pubmed-meshheading:18836731-Colorectal Neoplasms,
pubmed-meshheading:18836731-Demography,
pubmed-meshheading:18836731-Female,
pubmed-meshheading:18836731-Genetic Predisposition to Disease,
pubmed-meshheading:18836731-Humans,
pubmed-meshheading:18836731-Integrin alpha2,
pubmed-meshheading:18836731-Integrin beta3,
pubmed-meshheading:18836731-Male,
pubmed-meshheading:18836731-Middle Aged,
pubmed-meshheading:18836731-Polymorphism, Single Nucleotide
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pubmed:year |
2009
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pubmed:articleTitle |
Integrin alpha-2 and beta-3 gene polymorphisms and colorectal cancer risk.
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pubmed:affiliation |
Division of Oncology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria. armin.gerger@klinikum-graz.at
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pubmed:publicationType |
Journal Article
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