Linked Life Data

18580860

Source:http://linkedlifedata.com/resource/pubmed/id/18580860

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-6-26
pubmed:abstractText
Much controversy has surrounded both the pathological basis and the clinical utility of the metabolic syndrome. Key questions still revolve around the definition of this syndrome, its utility as a predictor of cardiovascular risk, and the treatment implications of diagnosis. The metabolic syndrome is associated with increased cardiovascular risk. However, the metabolic syndrome clearly underperforms compared with other, established prediction equations, such as the Framingham Risk Score and SCORE (Systemic COronary Risk Evaluation). Differences arise because the components are highly correlated (whereas other tools specifically include independent predictors) and because diagnosis is based on dichotomized variables. These facts, together with uncertain pathophysiology, mean that the metabolic syndrome in its current manifestation has limited utility for the diagnosis and treatment of cardiovascular disease. The syndrome has, however, served and continues to serve a useful purpose in raising awareness of the metabolic consequences of obesity, and as a spur for research into metabolic risk factor interactions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1743-4300
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
5 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S10-4
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Does the metabolic syndrome add to the diagnosis and treatment of cardiovascular disease?
pubmed:affiliation
Department of Clinical Pharmacology, University Medical Center, Groningen, The Netherlands. d.de.zeeuw@med.umcg.nl
pubmed:publicationType
Journal Article, Review