Source:http://linkedlifedata.com/resource/pubmed/id/18503205
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-5-26
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pubmed:abstractText |
Two new compounds, 4-(hydroxymethyl)-5-hydroxy-2H-pyran-2-one (1) and (5-hydroxy-2-oxo-2H-pyran-4-yl) methyl acetate (2), have been isolated from a marine-derived fungus Aspergillus flavus. Their structures were determined by spectroscopic data. Compound 1 induced the production of cAMP on GPR12 transfected CHO and HEK293 cells in a dose-dependent manner, which indicated 1 might be a possible ligand for GPR12.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
245-9
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pubmed:meshHeading |
pubmed-meshheading:18503205-Animals,
pubmed-meshheading:18503205-Aspergillus flavus,
pubmed-meshheading:18503205-CHO Cells,
pubmed-meshheading:18503205-Cricetinae,
pubmed-meshheading:18503205-Cricetulus,
pubmed-meshheading:18503205-Humans,
pubmed-meshheading:18503205-Magnetic Resonance Spectroscopy,
pubmed-meshheading:18503205-Pyrones,
pubmed-meshheading:18503205-Receptors, G-Protein-Coupled,
pubmed-meshheading:18503205-Spectrometry, Mass, Electrospray Ionization,
pubmed-meshheading:18503205-Water Microbiology
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pubmed:year |
2008
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pubmed:articleTitle |
Two new 5-hydroxy-2-pyrone derivatives isolated from a marine-derived fungus Aspergillus flavus.
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pubmed:affiliation |
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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