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pubmed-article:18430195pubmed:abstractTextDetails of the mechanisms and selection pressures that shape the emergence and development of complex biological systems, such as the human immune system, are poorly understood. A recent definition of a reference set of proteins essential for the human immunome, combined with information about protein interaction networks for these proteins, facilitates evolutionary study of this biological machinery.lld:pubmed
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pubmed-article:18430195pubmed:authorpubmed-author:VihinenMaunoMlld:pubmed
pubmed-article:18430195pubmed:authorpubmed-author:OrtutayCsabaClld:pubmed
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pubmed-article:18430195pubmed:dateRevised2010-9-22lld:pubmed
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pubmed-article:18430195pubmed:articleTitleEfficiency of the immunome protein interaction network increases during evolution.lld:pubmed
pubmed-article:18430195pubmed:affiliationInstitute of Medical Technology, FI-33014 University of Tampere, Finland. csaba.ortutay@uta.filld:pubmed
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