|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0036525,
umls-concept:C0087111,
umls-concept:C0205179,
umls-concept:C0210657,
umls-concept:C0282461,
umls-concept:C0684249,
umls-concept:C1442989,
umls-concept:C1517927,
umls-concept:C1522484
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2008-4-29
|
|
pubmed:abstractText |
This phase III randomized trial compared pemetrexed 500 mg/m(2) (P500) with pemetrexed 900 mg/m(2) (P900) to determine whether higher dosing benefits non-small-cell lung cancer (NSCLC) patients as second-line therapy.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1569-8041
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
939-45
|
|
pubmed:meshHeading |
pubmed-meshheading:18283036-Adult,
pubmed-meshheading:18283036-Aged,
pubmed-meshheading:18283036-Aged, 80 and over,
pubmed-meshheading:18283036-Antimetabolites, Antineoplastic,
pubmed-meshheading:18283036-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18283036-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:18283036-Dose-Response Relationship, Drug,
pubmed-meshheading:18283036-Drug Resistance, Neoplasm,
pubmed-meshheading:18283036-Female,
pubmed-meshheading:18283036-Glutamates,
pubmed-meshheading:18283036-Guanine,
pubmed-meshheading:18283036-Humans,
pubmed-meshheading:18283036-Lung Neoplasms,
pubmed-meshheading:18283036-Male,
pubmed-meshheading:18283036-Middle Aged,
pubmed-meshheading:18283036-Salvage Therapy
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
A randomized phase III trial comparing standard and high-dose pemetrexed as second-line treatment in patients with locally advanced or metastatic non-small-cell lung cancer.
|
|
pubmed:affiliation |
Cancer Centre, Queen Elizabeth Hospital, University Hospital Birmingham, Birmingham, UK. michael.cullen@uhb.nhs.uk
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study,
Clinical Trial, Phase III
|
