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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-3-17
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pubmed:abstractText |
The egg envelope is an extracellular matrix that surrounds oocytes. In frogs and mammals, a prominent feature of envelope modification following fertilization is the N-terminal proteolysis of the envelope glycoproteins, ZPA [ZP (zona pellucida) A]. It was proposed that ZPA N-terminal proteolysis leads to a conformational change in egg envelope glycoproteins, resulting in the prevention of polyspermy. Bufo arenarum VE (vitelline envelope) is made up of at least four glycoproteins: gp120 (glycoprotein 120), gp75, gp41 and gp38. The aim of the present study was to identify and characterize the baZPA (B. arenarum ZPA homologue). Also, our aim was to evaluate its integrity and functional significance during fertilization.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1768-322X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-30
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pubmed:meshHeading |
pubmed-meshheading:17973629-Acrosome Reaction,
pubmed-meshheading:17973629-Amino Acid Sequence,
pubmed-meshheading:17973629-Animals,
pubmed-meshheading:17973629-Antibodies,
pubmed-meshheading:17973629-Base Sequence,
pubmed-meshheading:17973629-Bufo arenarum,
pubmed-meshheading:17973629-Cell Adhesion,
pubmed-meshheading:17973629-Cloning, Molecular,
pubmed-meshheading:17973629-Egg Proteins,
pubmed-meshheading:17973629-Female,
pubmed-meshheading:17973629-Fertilization,
pubmed-meshheading:17973629-Fluorescent Antibody Technique,
pubmed-meshheading:17973629-In Situ Hybridization,
pubmed-meshheading:17973629-Male,
pubmed-meshheading:17973629-Membrane Glycoproteins,
pubmed-meshheading:17973629-Molecular Sequence Data,
pubmed-meshheading:17973629-Peptides,
pubmed-meshheading:17973629-RNA, Messenger,
pubmed-meshheading:17973629-Receptors, Cell Surface,
pubmed-meshheading:17973629-Sequence Homology,
pubmed-meshheading:17973629-Sperm-Ovum Interactions,
pubmed-meshheading:17973629-Vitelline Membrane
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pubmed:year |
2008
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pubmed:articleTitle |
Cellular origin of the Bufo arenarum sperm receptor gp75, a ZP2 family member: its proteolysis after fertilization.
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pubmed:affiliation |
División Biología del Desarrollo, IBR (CONICET-UNR) and Area Biología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario S2002RLK, Republic of Argentina.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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