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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1992-3-5
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pubmed:abstractText |
A total of 39 toxigenic and 20 nontoxigenic strains of Clostridium difficile were tested for the presence of either toxin A or toxin B by the polymerase chain reaction (PCR). All toxigenic strains produced cytotoxin as assayed by using highly sensitive fetal lung fibroblasts and were positive for toxin A as well as toxin B in the PCR assay. All nontoxigenic strains failed to produce toxin and were negative in the PCR assay. This study shows that nontoxigenic strains of Clostridium difficile lack the toxin A as well as the toxin B gene.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0095-1137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2666-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:1774285-Bacterial Proteins,
pubmed-meshheading:1774285-Bacterial Toxins,
pubmed-meshheading:1774285-Base Sequence,
pubmed-meshheading:1774285-Clostridium difficile,
pubmed-meshheading:1774285-DNA, Bacterial,
pubmed-meshheading:1774285-Enterotoxins,
pubmed-meshheading:1774285-Genes, Bacterial,
pubmed-meshheading:1774285-Humans,
pubmed-meshheading:1774285-Molecular Sequence Data,
pubmed-meshheading:1774285-Polymerase Chain Reaction
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pubmed:year |
1991
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pubmed:articleTitle |
Nontoxigenic strains of Clostridium difficile lack the genes for both toxin A and toxin B.
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pubmed:affiliation |
Eijkman Winkler Laboratory for Medical Microbiology, University Hospital Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article
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