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pubmed-article:17657162pubmed:abstractTextSmoking predisposes to the development of atherosclerosis and of its complications. The mechanisms responsible for these effects are not completely understood. We have investigated whether nicotine might promote a proatherosclerotic state in human coronary endothelial cells (HCAECs), studying the role of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in preventing these phenomena.lld:pubmed
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pubmed-article:17657162pubmed:articleTitleHMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells.lld:pubmed
pubmed-article:17657162pubmed:affiliationDivision of Cardiology, University of Naples Federico II, Naples, Italy. pcirillo@unina.itlld:pubmed
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