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rdf:type |
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lifeskim:mentions |
umls-concept:C0032214,
umls-concept:C0035820,
umls-concept:C0040661,
umls-concept:C0205087,
umls-concept:C0205390,
umls-concept:C0257694,
umls-concept:C0376466,
umls-concept:C0600138,
umls-concept:C0752312,
umls-concept:C0907532,
umls-concept:C1424650,
umls-concept:C1704259,
umls-concept:C1705987
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pubmed:issue |
5
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pubmed:dateCreated |
2007-7-31
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pubmed:abstractText |
The role of endothelial nitric oxide synthase (eNOS) in ischemic preconditioning (PC) and cardioprotection is poorly understood. We addressed this issue using a genetic, rather than pharmacological, approach.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1-hydroxy-2-oxo-3,3-bis(2-aminoethyl...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/DNA,
http://linkedlifedata.com/resource/pubmed/chemical/MAP Kinase Kinase Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/MAP Kinase Kinase Kinase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Map3k2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Donors,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase C-epsilon,
http://linkedlifedata.com/resource/pubmed/chemical/Ptgs2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/STAT1 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Stat1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Stat3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Triazenes
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
31
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pubmed:volume |
116
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
535-44
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pubmed:dateRevised |
2011-11-2
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pubmed:meshHeading |
pubmed-meshheading:17606840-Adaptation, Physiological,
pubmed-meshheading:17606840-Animals,
pubmed-meshheading:17606840-Cyclooxygenase 2,
pubmed-meshheading:17606840-DNA,
pubmed-meshheading:17606840-Enzyme Activation,
pubmed-meshheading:17606840-Enzyme Induction,
pubmed-meshheading:17606840-Hypertension,
pubmed-meshheading:17606840-Ischemic Preconditioning, Myocardial,
pubmed-meshheading:17606840-MAP Kinase Kinase Kinase 1,
pubmed-meshheading:17606840-MAP Kinase Kinase Kinase 2,
pubmed-meshheading:17606840-Mice,
pubmed-meshheading:17606840-Mice, Inbred C57BL,
pubmed-meshheading:17606840-Mice, Knockout,
pubmed-meshheading:17606840-Mice, Mutant Strains,
pubmed-meshheading:17606840-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:17606840-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:17606840-Myocardial Infarction,
pubmed-meshheading:17606840-Myocardial Reperfusion Injury,
pubmed-meshheading:17606840-Nitric Oxide,
pubmed-meshheading:17606840-Nitric Oxide Donors,
pubmed-meshheading:17606840-Nitric Oxide Synthase Type II,
pubmed-meshheading:17606840-Nitric Oxide Synthase Type III,
pubmed-meshheading:17606840-Phosphorylation,
pubmed-meshheading:17606840-Protein Kinase C-epsilon,
pubmed-meshheading:17606840-Protein Processing, Post-Translational,
pubmed-meshheading:17606840-STAT1 Transcription Factor,
pubmed-meshheading:17606840-STAT3 Transcription Factor,
pubmed-meshheading:17606840-Signal Transduction,
pubmed-meshheading:17606840-Specific Pathogen-Free Organisms,
pubmed-meshheading:17606840-Stress, Physiological,
pubmed-meshheading:17606840-Time Factors,
pubmed-meshheading:17606840-Triazenes
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pubmed:year |
2007
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pubmed:articleTitle |
Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pathway.
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pubmed:affiliation |
Institute of Molecular Cardiology, University of Louisville, Louisville, KY 40292, USA. ytxuan01@louisville.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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