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pubmed-article:1739521pubmed:abstractTextAny physician treating cardiac arrhythmias should be aware of a possible worsening of the arrhythmia (so-called arrhythmogenesis) after the start of antiarrhythmic drug treatment. To facilitate the recognition of that complication the type and possible mechanisms of arrhythmogenesis are reviewed. Recognition also requires an understanding of (a) the time of appearance of arrhythmogenic effects after different drugs, (b) the value of non-invasive and invasive tests, and (c) the profile of the patient most likely to develop this problem. Guidelines are given to reduce the incidence of the arrhythmogenic effects of antiarrhythmic drugs and a plea is made that the physician should be always on the alert for this complication.lld:pubmed
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pubmed-article:1739521pubmed:authorpubmed-author:WellensH JHJlld:pubmed
pubmed-article:1739521pubmed:authorpubmed-author:GorgelsA PAPlld:pubmed
pubmed-article:1739521pubmed:authorpubmed-author:SmeetsJ LJLlld:pubmed
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pubmed-article:1739521pubmed:pagination25-33lld:pubmed
pubmed-article:1739521pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:1739521pubmed:year1992lld:pubmed
pubmed-article:1739521pubmed:articleTitleAntiarrhythmic drug treatment: need for continuous vigilance.lld:pubmed
pubmed-article:1739521pubmed:affiliationDepartment of Cardiology, Academic Hospital Maastricht, University of Limburg, The Netherlands.lld:pubmed
pubmed-article:1739521pubmed:publicationTypeJournal Articlelld:pubmed
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