Source:http://linkedlifedata.com/resource/pubmed/id/17346077
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2007-4-27
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pubmed:abstractText |
A new meroditerpene, (+)-isojaspic acid (1), along with two known meroditerpenes, cacospongin D (2) and jaspaquinol (3), have been isolated from a marine sponge Cacospongia. Comprehensive taxonomic identification distinguished this Cacospongia apart from morphologically similar Psammocinia. The absolute stereochemistry of 1 was elucidated on the basis of extensive 1D and 2D NMR techniques and analysis of the optical rotation versus (+)-zonarol (8), (+)-isozonarol (9), (-)-dactylosponol (10), and (+)-hyatellaquinone (11). Furthermore, bioactivity evaluation showed that the meroditerpenes isolated significantly inhibited Staphylococcus epidermidis.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
628-31
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17346077-Animals,
pubmed-meshheading:17346077-Anti-Bacterial Agents,
pubmed-meshheading:17346077-Diterpenes,
pubmed-meshheading:17346077-Marine Biology,
pubmed-meshheading:17346077-Microbial Sensitivity Tests,
pubmed-meshheading:17346077-Molecular Structure,
pubmed-meshheading:17346077-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:17346077-Papua New Guinea,
pubmed-meshheading:17346077-Photography,
pubmed-meshheading:17346077-Porifera,
pubmed-meshheading:17346077-Staphylococcus epidermidis,
pubmed-meshheading:17346077-Stereoisomerism
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pubmed:year |
2007
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pubmed:articleTitle |
Extending the record of meroditerpenes from Cacospongia marine sponges.
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pubmed:affiliation |
Department of Chemistry and Biochemistry and Institute for Marine Sciences, University of California Santa Cruz, Santa Cruz, California 95064, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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