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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0021655,
umls-concept:C0123658,
umls-concept:C0185117,
umls-concept:C0205054,
umls-concept:C0220847,
umls-concept:C0332161,
umls-concept:C0449297,
umls-concept:C0542341,
umls-concept:C1334140,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2007-3-5
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pubmed:abstractText |
Hepatitis C virus (HCV) infection is linked to greater insulin resistance. Although HCV itself is a candidate for the development of insulin resistance, the effects of antiviral treatment on impaired glucose metabolism remain unclear. The aim of this study is to examine the effects of clearance of HCV on insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate (IRS)1/2, central molecules for insulin signaling.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/IRS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/IRS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin Receptor Substrate Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Intracellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Insulin
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-9270
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pubmed:author |
pubmed-author:HanadaShinichiroS,
pubmed-author:HiranoEiichiE,
pubmed-author:IdeTatsuyaT,
pubmed-author:ItouMinoruM,
pubmed-author:KawaguchiTakumiT,
pubmed-author:KogaHironoriH,
pubmed-author:NagaoYumikoY,
pubmed-author:SataMichioM,
pubmed-author:SumieShujiS,
pubmed-author:TaniguchiEitaroE,
pubmed-author:YanagimotoChikatoshiC
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pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
570-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17222321-Biopsy,
pubmed-meshheading:17222321-Female,
pubmed-meshheading:17222321-Follow-Up Studies,
pubmed-meshheading:17222321-Gene Expression,
pubmed-meshheading:17222321-Hepacivirus,
pubmed-meshheading:17222321-Hepatitis C,
pubmed-meshheading:17222321-Humans,
pubmed-meshheading:17222321-Immunoblotting,
pubmed-meshheading:17222321-Immunohistochemistry,
pubmed-meshheading:17222321-Insulin Receptor Substrate Proteins,
pubmed-meshheading:17222321-Insulin Resistance,
pubmed-meshheading:17222321-Insulin-Secreting Cells,
pubmed-meshheading:17222321-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:17222321-Liver,
pubmed-meshheading:17222321-Male,
pubmed-meshheading:17222321-Middle Aged,
pubmed-meshheading:17222321-Phosphoproteins,
pubmed-meshheading:17222321-Prognosis,
pubmed-meshheading:17222321-RNA, Viral,
pubmed-meshheading:17222321-Receptor, Insulin,
pubmed-meshheading:17222321-Viral Load
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pubmed:year |
2007
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pubmed:articleTitle |
Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.
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pubmed:affiliation |
Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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