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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-16
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pubmed:abstractText |
Recent studies in murine models of allergic contact dermatitis have shown that systemic treatment with pimecrolimus in contrast to tacrolimus did not inhibit the sensitization phase, whereas both compounds equivalently suppressed the inflammatory response in sensitized animals. This finding indicated a differential sensitivity of antigen-naïve and primed T cells towards pimecrolimus and tacrolimus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1018-2438
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
142
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
255-64
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pubmed:meshHeading |
pubmed-meshheading:17114891-Cell Line,
pubmed-meshheading:17114891-Cell Proliferation,
pubmed-meshheading:17114891-Cytokines,
pubmed-meshheading:17114891-Dendritic Cells,
pubmed-meshheading:17114891-Dermatitis, Atopic,
pubmed-meshheading:17114891-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:17114891-Humans,
pubmed-meshheading:17114891-Immunosuppressive Agents,
pubmed-meshheading:17114891-Jurkat Cells,
pubmed-meshheading:17114891-Lymphocyte Activation,
pubmed-meshheading:17114891-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:17114891-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17114891-T-Lymphocytes,
pubmed-meshheading:17114891-Tacrolimus
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pubmed:year |
2007
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pubmed:articleTitle |
Differential inhibition of primary versus preactivated T cells by pimecrolimus but not by tacrolimus in vitro.
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pubmed:affiliation |
Novartis Institutes for Biomedical Research, Vienna, Austria. frank.kalthoff@novartis.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
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