Linked Life Data

16890580

Source:http://linkedlifedata.com/resource/pubmed/id/16890580

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-8-7
pubmed:abstractText
Our objective was to explore the relationships between imatinib pharmacokinetics and 9 allelic variants in 7 genes coding for adenosine triphosphate-binding cassette transporters (ABCB1 and ABCG2) and enzymes (cytochrome P450 [CYP] 2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5) of putative relevance for imatinib.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0009-9236
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
192-201
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:16890580-ATP-Binding Cassette Transporters, pubmed-meshheading:16890580-Adult, pubmed-meshheading:16890580-Aged, pubmed-meshheading:16890580-Aged, 80 and over, pubmed-meshheading:16890580-Alleles, pubmed-meshheading:16890580-Biological Transport, Active, pubmed-meshheading:16890580-Carrier Proteins, pubmed-meshheading:16890580-Cell Line, Tumor, pubmed-meshheading:16890580-Cohort Studies, pubmed-meshheading:16890580-Cytochrome P-450 Enzyme System, pubmed-meshheading:16890580-Female, pubmed-meshheading:16890580-Gastrointestinal Neoplasms, pubmed-meshheading:16890580-Gene Frequency, pubmed-meshheading:16890580-Genotype, pubmed-meshheading:16890580-Humans, pubmed-meshheading:16890580-Isoenzymes, pubmed-meshheading:16890580-Male, pubmed-meshheading:16890580-Middle Aged, pubmed-meshheading:16890580-Pharmaceutical Preparations, pubmed-meshheading:16890580-Phenotype, pubmed-meshheading:16890580-Piperazines, pubmed-meshheading:16890580-Protein-Tyrosine Kinases, pubmed-meshheading:16890580-Proto-Oncogene Proteins c-kit, pubmed-meshheading:16890580-Pyrimidines, pubmed-meshheading:16890580-Stromal Cells
pubmed:year
2006
pubmed:articleTitle
Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib.
pubmed:affiliation
Clinical Pharmacology Research Core, SAIC-Frederick, Frederick, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural