Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-1-17
pubmed:abstractText
A polymorphism of the switch region of the mu IgH gene (S mu) is associated with arthritis in English patients with psoriasis. In this study, Italian patients with psoriasis alone (PS) or psoriatic arthritis (PSA) were analysed by Southern blot using DNA probes for the S mu region and a hypervariable locus 5' of the joining (JH) region of IgH (5' JH). No association between PSA and IgH gene polymorphisms was found. However, an association was found between PS and a genotype of the 5' JH region (Fisher's P = 0.0002, RR = 27). Additional DNA markers around the S mu region may reveal more accurate markers for PS or PSA.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0263-7103
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:geneSymbol
S&mgr;
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
449-50
pubmed:dateRevised
2009-9-29
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Immunoglobulin heavy chain gene polymorphisms in Italian patients with psoriasis and psoriatic arthritis.
pubmed:affiliation
Molecular Immunogenetics Unit, UMDS, Guy's Hospital, London.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't