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pubmed-article:16565212pubmed:abstractTextTemozolomide is an oral alkylating agent that crosses the blood-brain barrier, and has preclinical activity in breast cancer. This phase II trial sought to determine the activity and toxicity of temozolomide in metastatic breast cancer (MBC). Temozolomide was administered in a dose dense schedule of 150 mg/m(2) on days 1-7 and 15-21 in a 28-day cycle.lld:pubmed
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pubmed-article:16565212pubmed:articleTitleTemozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada - Clinical Trials Group (NCIC-CTG).lld:pubmed
pubmed-article:16565212pubmed:affiliationToronto Sunnybrook Regional Cancer Centre, ON, Canada. Maureen.Trudeau@sw.calld:pubmed
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