rdf:type |
|
lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0020835,
umls-concept:C0039005,
umls-concept:C0042196,
umls-concept:C0079460,
umls-concept:C0205263,
umls-concept:C0205369,
umls-concept:C0229671,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
21
|
pubmed:dateCreated |
2006-6-1
|
pubmed:abstractText |
We have used FaeG DNA to immunise piglets by the intradermal (ID) and the intramuscular (IM) route in a heterologous prime/boost model. ID immunisation with DNA resulted in a better induction of cellular immunity, whereas only the IM immunisation could prime an F4(K88)-specific serum IgA response. However, ID administration of plasmid-encoded GM-CSF 1 week before the ID immunisation enhanced the F4-specific humoral and cellular immune response and even primed the F4-specific IgA response more efficiently than the IM immunisation did.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0264-410X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
22
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4592-4
|
pubmed:meshHeading |
|
pubmed:year |
2006
|
pubmed:articleTitle |
Plasmid-encoded GM-CSF induces priming of the F4(K88)-specific serum IgA response by FaeG DNA vaccination in pigs.
|
pubmed:affiliation |
Laboratory of Veterinary Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Vesna.Melkebeek@ugent.be
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|