|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2005-2-21
|
|
pubmed:abstractText |
The serotonin transporter (5-HTT) and tryptophan hydroxylase (TPH) gene are important candidate genes for the psychiatric disorders. Many studies of patients with anxiety disorders have found abnormalities of serotonin metabolism and dysfunction of regulation in the transporter itself. In this study, we hypothesize that genetic variation in the 5-HTT and TPH gene may have an effect on the etiology of generalized anxiety disorder (GAD).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0955-8829
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
15
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
7-11
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15722951-Adult,
pubmed-meshheading:15722951-Anxiety Disorders,
pubmed-meshheading:15722951-Asian Continental Ancestry Group,
pubmed-meshheading:15722951-China,
pubmed-meshheading:15722951-DNA,
pubmed-meshheading:15722951-Female,
pubmed-meshheading:15722951-Gene Frequency,
pubmed-meshheading:15722951-Genotype,
pubmed-meshheading:15722951-Humans,
pubmed-meshheading:15722951-Introns,
pubmed-meshheading:15722951-Male,
pubmed-meshheading:15722951-Membrane Glycoproteins,
pubmed-meshheading:15722951-Membrane Transport Proteins,
pubmed-meshheading:15722951-Mutagenesis, Insertional,
pubmed-meshheading:15722951-Nerve Tissue Proteins,
pubmed-meshheading:15722951-Polymerase Chain Reaction,
pubmed-meshheading:15722951-Polymorphism, Genetic,
pubmed-meshheading:15722951-Reference Values,
pubmed-meshheading:15722951-Sequence Deletion,
pubmed-meshheading:15722951-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:15722951-Tryptophan Hydroxylase
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Serotonin transporter and tryptophan hydroxylase gene polymorphisms in Chinese patients with generalized anxiety disorder.
|
|
pubmed:affiliation |
Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, Hunan, P.R. China.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
