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pubmed-article:15609771pubmed:abstractTextEvidence indicates that cysteinyl leukotriene (cysLT) 1 receptor antagonists possess anti-inflammatory properties in asthmatic patients in vivo. Although the exact mechanisms of these actions remain unknown, cysLTs regulate the locomotion and functions of eosinophils. We previously reported that leukotriene D4 augments the expression of eosinophil beta2 integrin and the adhesion of eosinophils to rh intercellular adhesion molecule 1 via beta2 integrin.lld:pubmed
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pubmed-article:15609771pubmed:articleTitleLeukotriene D4 and eosinophil transendothelial migration, superoxide generation, and degranulation via beta2 integrin.lld:pubmed
pubmed-article:15609771pubmed:affiliationDepartment of Respiratory Medicine, Saitama Medical School, Saitama, Japan.lld:pubmed
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pubmed-article:15609771pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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