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pubmed-article:15183593pubmed:abstractTextImidazoline derivatives like naphazoline have a firm place in diagnostics and therapy of otorhinolaryngology because of their vasoconstrictive and decongestive properties. Their alpha-adrenergic potential could induce not only local but also systemic side effects like hypertension and tachycardia which can increase a life-threatening intoxication. Signs of imidazoline intoxication are excessive systolic and diastolic hypertension and hypotension, bradycardia with arrhythmia, respiratory depression, excitation or severe CNS depression.lld:pubmed
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pubmed-article:15183593pubmed:articleTitleCourse and therapy of intoxication with imidazoline derivate naphazoline.lld:pubmed
pubmed-article:15183593pubmed:affiliationDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany. swenzel@uke.uni-hamburg.delld:pubmed
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