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rdf:type |
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lifeskim:mentions |
umls-concept:C0024487,
umls-concept:C0025260,
umls-concept:C0205098,
umls-concept:C0205307,
umls-concept:C0205653,
umls-concept:C0439849,
umls-concept:C0442043,
umls-concept:C0445223,
umls-concept:C0597198,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
4
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pubmed:dateCreated |
2004-4-19
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|
pubmed:abstractText |
In addition to the study of pathological conditions, magnetic resonance spectroscopy can provide useful information about brain-behavior relationships in normal subjects. Recently, there have been reports of correlations between N-acetylaspartate (NAA) values and cognitive functions in normal adults. We tested the possible specific relationship between the NAA/choline (Cho) ratio in the medial temporal lobe and memory performance in normal adolescents. The medial temporal NAA/Cho ratio was unrelated to age, gender and general intelligence but presented a clear correlation with several memory measures. In the regression analysis two memory variables (RAVLT learning and a face-name recognition task) explained 55.6% of NAA/Cho variance. We conclude that NAA values in the medial temporal lobe are related to memory abilities but not to global intelligence in normal adolescent subjects.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0959-4965
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
703-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15094480-Adolescent,
pubmed-meshheading:15094480-Age Factors,
pubmed-meshheading:15094480-Aspartic Acid,
pubmed-meshheading:15094480-Brain Chemistry,
pubmed-meshheading:15094480-Brain Mapping,
pubmed-meshheading:15094480-Child,
pubmed-meshheading:15094480-Choline,
pubmed-meshheading:15094480-Female,
pubmed-meshheading:15094480-Humans,
pubmed-meshheading:15094480-Intelligence,
pubmed-meshheading:15094480-Magnetic Resonance Spectroscopy,
pubmed-meshheading:15094480-Male,
pubmed-meshheading:15094480-Memory,
pubmed-meshheading:15094480-Neuropsychological Tests,
pubmed-meshheading:15094480-Recognition (Psychology),
pubmed-meshheading:15094480-Reference Values,
pubmed-meshheading:15094480-Regression Analysis,
pubmed-meshheading:15094480-Sex Factors,
pubmed-meshheading:15094480-Temporal Lobe
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pubmed:year |
2004
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pubmed:articleTitle |
Medial temporal MR spectroscopy is related to memory performance in normal adolescent subjects.
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pubmed:affiliation |
Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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