|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2004-4-5
|
|
pubmed:abstractText |
Inhaled fluticasone propionate (FP) therapy decreases inflammation and sub-basement membrane thickness in asthmatic airways. Bronchiolitis obliterans syndrome (BOS) in lung transplant recipients (LTRs) involves progressive airway fibrosis and obliteration. Therefore, augmented immunosuppression may be of some benefit in treating BOS. In this study, we examined the effect of 3 months of treatment with high-dose inhaled FP on the concentrations of 2 fibrogenic factors, transforming growth factor (TGF)-beta(1) and beta fibrogenic growth factor (bFGF) in bronchoalveolar lavage (BAL) fluid from clinically stable LTRs.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1053-2498
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
446-55
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15063404-Administration, Inhalation,
pubmed-meshheading:15063404-Adult,
pubmed-meshheading:15063404-Androstadienes,
pubmed-meshheading:15063404-Anti-Inflammatory Agents,
pubmed-meshheading:15063404-Bronchiolitis Obliterans,
pubmed-meshheading:15063404-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:15063404-Dose-Response Relationship, Drug,
pubmed-meshheading:15063404-Double-Blind Method,
pubmed-meshheading:15063404-Female,
pubmed-meshheading:15063404-Fibroblast Growth Factors,
pubmed-meshheading:15063404-Humans,
pubmed-meshheading:15063404-Immunosuppression,
pubmed-meshheading:15063404-Lung,
pubmed-meshheading:15063404-Lung Transplantation,
pubmed-meshheading:15063404-Male,
pubmed-meshheading:15063404-Middle Aged,
pubmed-meshheading:15063404-Respiratory Function Tests,
pubmed-meshheading:15063404-Transforming Growth Factor beta,
pubmed-meshheading:15063404-Transforming Growth Factor beta1
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Effect of inhaled fluticasone propionate on BAL TGF-beta(1) and bFGF concentrations in clinically stable lung transplant recipients.
|
|
pubmed:affiliation |
Department of Respiratory Medicine, Alfred Hospital and Monash University Medical School, Melbourne, Australia.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
