Source:http://linkedlifedata.com/resource/pubmed/id/14715075
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-1-12
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pubmed:abstractText |
An assessment of burn depth is a key step in guiding the treatment of patients who have sustained thermal injuries. Polarization-sensitive optical coherence tomography (PS-OCT) might eventually provide the physician with a quantitative estimate of actual burn depth. Burns of various depths were induced by contacting rat skin with a brass rod preheated to 75 degrees C for 5, 15, or 30 s. Thermal injury denatured the collagen in the skin, and PS-OCT imaged the resulting reduction of birefringence through the depth-resolved changes in the polarization state of light propagated and reflected from the sample. Stokes vectors were calculated for each point in the PS-OCT images and the reduction in the rate of phase retardation between two orthogonal polarizations of light (deg/microm) was found to show a consistent trend with burn exposure time. PS-OCT is a noninvasive technique with potential to give the physician the information needed to formulate an optimal treatment plan for burn patients.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1083-3668
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2004 Society of Photo-Optical Instrumentation Engineers.
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-12
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14715075-Animals,
pubmed-meshheading:14715075-Burns,
pubmed-meshheading:14715075-Diagnosis, Computer-Assisted,
pubmed-meshheading:14715075-Female,
pubmed-meshheading:14715075-Interferometry,
pubmed-meshheading:14715075-Microscopy, Polarization,
pubmed-meshheading:14715075-Photometry,
pubmed-meshheading:14715075-Rats,
pubmed-meshheading:14715075-Rats, Sprague-Dawley,
pubmed-meshheading:14715075-Reproducibility of Results,
pubmed-meshheading:14715075-Sensitivity and Specificity,
pubmed-meshheading:14715075-Tomography, Optical Coherence,
pubmed-meshheading:14715075-Trauma Severity Indices
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pubmed:articleTitle |
Determination of burn depth by polarization-sensitive optical coherence tomography.
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pubmed:affiliation |
Beckman Laser Institute, Department of Biomedical Engineering and Surgery, University of California-Irvine, Irvine, CA 92612, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Validation Studies
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