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| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C0040077 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C0021044 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C1548779 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C1947902 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C2827499 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C1167624 | lld:lifeskim |
| pubmed-article:1381560 | lifeskim:mentions | umls-concept:C0336867 | lld:lifeskim |
| pubmed-article:1381560 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1381560 | pubmed:dateCreated | 1992-10-7 | lld:pubmed |
| pubmed-article:1381560 | pubmed:abstractText | The authors compared detection of proliferating vascular smooth muscle cells (SMC) in vitro and in vivo with proliferating cell nuclear antigen (PCNA) immunohistochemistry and two established methods: [3H]thymidine autoradiography and bromodeoxyuridine immunohistochemistry. Labeling with [3H]thymidine and bromodeoxyuridine of rat vascular SMC in culture stained 11% +/- 2% and 11% +/- 1% of cells, and PCNA immunohistochemistry 22% +/- 2% of cells. Proliferation in the media of the denuded rat aortae was highest 3 days after denudation: 4.2%, 3.8%, and 4.7% of labeled cells with [3H]thymidine, bromodeoxyuridine, and PCNA, respectively. In the intima, proliferation was highest 7 days after denudation with 42% [3H]thymidine, 40% bromodeoxyuridine, and 46% PCNA-positive cells. With double labeling, all [3H]thymidine-positive cells were PCNA positive, whereas some cells were only positive for PCNA. The authors conclude that PCNA immunohistochemistry compares favorably with [3H]thymidine autoradiography, and bromodeoxyuridine immunohistochemistry. | lld:pubmed |
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| pubmed-article:1381560 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1381560 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1381560 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:1381560 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1381560 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1381560 | pubmed:issn | 0002-9440 | lld:pubmed |
| pubmed-article:1381560 | pubmed:author | pubmed-author:FishbeinM CMC | lld:pubmed |
| pubmed-article:1381560 | pubmed:author | pubmed-author:CercekBB | lld:pubmed |
| pubmed-article:1381560 | pubmed:author | pubmed-author:ForresterJ... | lld:pubmed |
| pubmed-article:1381560 | pubmed:author | pubmed-author:ZeymerUU | lld:pubmed |
| pubmed-article:1381560 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1381560 | pubmed:volume | 141 | lld:pubmed |
| pubmed-article:1381560 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1381560 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1381560 | pubmed:pagination | 685-90 | lld:pubmed |
| pubmed-article:1381560 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:1381560 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1381560 | pubmed:articleTitle | Proliferating cell nuclear antigen immunohistochemistry in rat aorta after balloon denudation. Comparison with thymidine and bromodeoxyuridine labeling. | lld:pubmed |
| pubmed-article:1381560 | pubmed:affiliation | Division of Cardiology, Cedars Sinai Medical Center, Los Angeles, California 90048-0750. | lld:pubmed |
| pubmed-article:1381560 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1381560 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1381560 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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