Linked Life Data

12820281

Source:http://linkedlifedata.com/resource/pubmed/id/12820281

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2003-6-23
pubmed:abstractText
We advocate that medical diagnostic tests should be evaluated at the subunit level instead of the patient level if a disease can occur in multiple parts/units within a patient, for example, vessels, segments, ears, eyes etc. When a non-invasive test is compared to an invasive gold standard test, often not all of the subunits receive the gold standard test and verification bias is present if the subunits without the gold standard test are discarded. Here we address estimation and inference issues in assessing the performance of medical diagnostic tests at the subunit level while accounting for verification bias and the correlation among subunits. We present a weighted least squares approach and demonstrate how the method can be implemented by using the procedure PROC CATMOD from the popular SAS software. A cardiology example is presented and we discuss application of the method to the case of multiple tests and a single gold standard test.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0277-6715
pubmed:author
pubmed:copyrightInfo
CopyrightCopyright 2003 John Wiley & Sons, Ltd.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2161-76
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Evaluating medical diagnostic tests at the subunit level in the presence of verification bias.
pubmed:affiliation
Department of Biostatistics, The Rollins School of Public Health of Emory University, 1518 Clifton Road, NE Atlanta, Georgia 30322, USA. hbarnha@sph.emory.edu
pubmed:publicationType
Journal Article