Linked Life Data

12690623

Source:http://linkedlifedata.com/resource/pubmed/id/12690623

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-4-14
pubmed:abstractText
Chemotherapeutic agents operate through a number of different mechanisms; not all of them depend on ROS for their cytotoxic activity. Drugs with pharmacologic action that do not depend on ROS also are available; these are less susceptible to possible interference by antioxidants. In addition, caution should be exercised with investigational drugs whose mechanisms are being explored (Labriola & Livingston, 1999). Regardless, without studies specifically evaluating the impact that antioxidants have on cancer therapies, one still cannot confidently advise patients with cancer to supplement their diet with large doses of antioxidants for potential anticancer and protectant effects. It has been scientifically supported that antioxidants have a beneficial effect on reducing extraneous oxidative damage; so, based on what is known to date, an antioxidant-rich diet seems to be the most prudent advice when confronted with the advisability of supplementation during cancer therapy. In the near future, it is hoped that studies will further define the relationship between the many different cancer diseases, treatments, and supplemental antioxidants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
N
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1092-1095
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-2
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Antioxidant supplements during cancer treatments: where do we stand?
pubmed:affiliation
Teachers College, Columbia University, New York, NY, USA.
pubmed:publicationType
Journal Article, Review