| pubmed-article:12672258 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C1979963 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C0443199 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C1518591 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C2003903 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:12672258 | lifeskim:mentions | umls-concept:C0134427 | lld:lifeskim |
| pubmed-article:12672258 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:12672258 | pubmed:dateCreated | 2003-4-3 | lld:pubmed |
| pubmed-article:12672258 | pubmed:abstractText | The 14-amino analogue of oxymorphindole (OMI) was synthesized and found to possess delta-opioid binding affinity and selectivity similar to OMI. Substitution of the amino group with alkyl, arylalkyl, and acyl groups had relatively little effect on delta-affinity but delta-selectivity was reduced. In functional assays the 14-phenylacetylamino derivative 6d was a selective delta-agonist whereas the phenethylamino analogue 5d was a mu-agonist and low efficacy delta partial agonist that warrants further investigation as an analgesic with low tolerance and dependence. | lld:pubmed |
| pubmed-article:12672258 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12672258 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12672258 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12672258 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12672258 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12672258 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:12672258 | pubmed:author | pubmed-author:TraynorJohn... | lld:pubmed |
| pubmed-article:12672258 | pubmed:author | pubmed-author:HusbandsSteph... | lld:pubmed |
| pubmed-article:12672258 | pubmed:author | pubmed-author:LewisJohn WJW | lld:pubmed |
| pubmed-article:12672258 | pubmed:author | pubmed-author:JalesAndrew... | lld:pubmed |
| pubmed-article:12672258 | pubmed:author | pubmed-author:GrundtPeterP | lld:pubmed |
| pubmed-article:12672258 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12672258 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:12672258 | pubmed:volume | 46 | lld:pubmed |
| pubmed-article:12672258 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12672258 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12672258 | pubmed:pagination | 1563-6 | lld:pubmed |
| pubmed-article:12672258 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:meshHeading | pubmed-meshheading:12672258... | lld:pubmed |
| pubmed-article:12672258 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12672258 | pubmed:articleTitle | 14-amino, 14-alkylamino, and 14-acylamino analogs of oxymorphindole. Differential effects on opioid receptor binding and functional profiles. | lld:pubmed |
| pubmed-article:12672258 | pubmed:affiliation | Department of Pharmacy and Pharmacology, University of Bath, UK. | lld:pubmed |
| pubmed-article:12672258 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12672258 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:12672258 | lld:chembl |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12672258 | lld:pubmed |
