Source:http://linkedlifedata.com/resource/pubmed/id/12465946
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
49
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pubmed:dateCreated |
2002-12-5
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pubmed:abstractText |
Purmorphamine, which is a 2,6,9-trisubstituted purine compound, was discovered through cell-based high-throughput screening from a heterocycle combinatorial library. It differentiates multipotent mesenchymal progenitor cells into an osteoblast lineage. It will serve as a unique chemical tool to study the molecular mechanisms of osteogenesis of stem cells and bone development.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-7863
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
14520-1
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pubmed:dateRevised |
2008-1-17
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pubmed:meshHeading |
pubmed-meshheading:12465946-Alkaline Phosphatase,
pubmed-meshheading:12465946-Animals,
pubmed-meshheading:12465946-Cell Differentiation,
pubmed-meshheading:12465946-Combinatorial Chemistry Techniques,
pubmed-meshheading:12465946-Mesoderm,
pubmed-meshheading:12465946-Mice,
pubmed-meshheading:12465946-Mice, Inbred C3H,
pubmed-meshheading:12465946-Morpholines,
pubmed-meshheading:12465946-Osteoblasts,
pubmed-meshheading:12465946-Osteogenesis,
pubmed-meshheading:12465946-Purines,
pubmed-meshheading:12465946-Stem Cells
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pubmed:year |
2002
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pubmed:articleTitle |
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells.
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pubmed:affiliation |
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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