|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0005390,
umls-concept:C0015733,
umls-concept:C0042105,
umls-concept:C0043047,
umls-concept:C0392747,
umls-concept:C0441655,
umls-concept:C0443172,
umls-concept:C0486616,
umls-concept:C0814861,
umls-concept:C1280500,
umls-concept:C1708335
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2002-9-16
|
|
pubmed:abstractText |
Ursodeoxycholic acid (UDCA) has been shown to affect membrane-damaging effects of bile acids in vitro and fecal bile acid composition in rats. This study evaluates the effect of UDCA on fecal bile acid composition and on cytolytic activity of fecal water in man to clarify the potential chemopreventive role of UDCA for colorectal cancer.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0036-5521
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
37
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
965-71
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12229974-Administration, Oral,
pubmed-meshheading:12229974-Adult,
pubmed-meshheading:12229974-Bile Acids and Salts,
pubmed-meshheading:12229974-Cholagogues and Choleretics,
pubmed-meshheading:12229974-Chromatography, Gas,
pubmed-meshheading:12229974-Chromatography, High Pressure Liquid,
pubmed-meshheading:12229974-Colorectal Neoplasms,
pubmed-meshheading:12229974-Cross-Over Studies,
pubmed-meshheading:12229974-Double-Blind Method,
pubmed-meshheading:12229974-Feces,
pubmed-meshheading:12229974-Female,
pubmed-meshheading:12229974-Hemolysis,
pubmed-meshheading:12229974-Humans,
pubmed-meshheading:12229974-Male,
pubmed-meshheading:12229974-Middle Aged,
pubmed-meshheading:12229974-Reference Values,
pubmed-meshheading:12229974-Risk Factors,
pubmed-meshheading:12229974-Ursodeoxycholic Acid
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
Changes in bile acid composition and effect on cytolytic activity of fecal water by ursodeoxycholic acid administration: a placebo-controlled cross-over intervention trial in healthy volunteers.
|
|
pubmed:affiliation |
Dept of Gastroenterology, University Hospital, Groningen, The Netherlands.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
