Linked Life Data

11978410

Source:http://linkedlifedata.com/resource/pubmed/id/11978410

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-4-29
pubmed:abstractText
The purpose of our study was to quantify renal transplant parenchymal sonographic enhancement using pulse-inversion imaging (PII) and intermittent emission after contrast administration by means of bolus and infusion techniques, and to evaluate renal perfusion functional indices. A total of 34 patients, presenting with minor abnormalities (n = 14) and cortical perfusion changes due to parenchymal disorders (n = 12) or renal artery stenosis (n = 8) were included. Cardiac-triggered contrast-enhanced PII ultrasound (US) was performed after administration of SHU 508 A (Schering AG, Berlin, Germany), using a high mechanical index, a frame rate of one image every four cardiac cycles for bolus study, and a decreasing frame rate for infusion study. Compared to baseline values, peak enhancement ratio ranged from 5.6 to 14.7 using a bolus administration, and reached a value of 2.1 to 4.0 using infusion technique. Qualitative analysis showed heterogeneous enhancement in most allografts presenting with acute parenchymal disease (p = 0.03). In bolus studies, time to peak, wash-in and wash-out slopes increased in renal transplants with parenchymal disease and renal artery stenosis (p = 0.0001). Infusion administration exhibited no plateau in signal level, and no significant difference in enhancement ratio was found between groups of patients. Triggered PII after contrast agent administration provides morphologic and quantitative information about cortical vascularity in renal transplants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0301-5629
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
303-14
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Contrast-enhanced sonography of the renal transplant using triggered pulse-inversion imaging: preliminary results.
pubmed:affiliation
Department of Radiology, University Hospital of Brabois, Vandoeuvre les Nancy, France
pubmed:publicationType
Journal Article